Kaiqiang Li

• Bsc Biomedical Sciences
• The roles of Ric1, a protein involved in Golgi transport, and Ost4, an ER membrane protein, in telomere defective strains

Telomere length shortens with age, and has been associated with increased incidence of age-related diseases. Also, recent studies suggested changes in morphology and function of cellular organelles in age-related disease cells. Previous Quantitative Fitness Analysis results from the Lydall lab shown some cellular organelle membrane proteins are involved in telomere function. This project aims to determine the roles of two membrane proteins, Ric1 and Ost4, in telomere uncapped Saccharomyces cerevisiae strains. Understanding the roles of these two proteins in telomere function will help better understanding of ageing mechanisms, and may provide a support for age-related diseases treatment development.

Project Supervisor: Prof David Lydall, Institute for Cell & Molecular Biosciences

Funding source: Genetics Society