Rikki Bobal

• MBBS
• Do novel rho-kinase inhibitor drugs alter the cell cycle duration of HeLa cells, and through what mechanism do they achieve this?

Rho-kinase inhibitor drugs 962B and Y-2 increased the duration of the HeLa cell cycle, reducing their rate of growth. This data suggests that 962B mediates this by promoting cell death of HeLa cells, and Y-2 acts to arrest cells immediately before they divide. HA-1077 was shown to have no significant effect on the HeLa cells. Limited availability of the microscope, and limited amounts of drug resulted in limited reliability of the data

Funding Source: INSPIRE