Jas Min Chin

• BSc (Hons) Biomedical Sciences
• Does localisation of DAP3 in the cytosol act as a trigger for apoptosis?

Mitochondria are constituents (organelles) of every cell in the human body. They play many important roles, but are the source of fuel that powers the body. About 1:5000 people have a mitochondrial deficiency that causes a loss in the production of this fuel and this can lead to death of cells and eventually of the individual. This loss of fuel is obviously very important for the body, but evidence is accumulating to suggest that the cell may die even before the lack of fuel production becomes a problem. How does this happen? Jas Min Chin will investigate.

Funding source: Newcastle University