2014 participants
Hyun Woo Yu
Mortality secondary to Hepatocellular cancer (HCC) is increasing significantly in England. This is partly due to the lack of effective screening tools available for early detection of the cancers, which consequently limits the chance of offering curative treatments. In this project, expression patterns of two candidate biomarkers (SULF2 and β-catenin) in HCC cell lines (Hep3B, Huh-7, SNU182 and SNU475) and patient blood samples were investigated using ImageStream and IDEAS software (Amnis, Seattle). Both biomarkers were found to have the potential to be used in a non-invasive screening tool, which aims to detect circulating tumour cells in HCC patients.
Funding Source: INSPIRE