Natalie Kimberly Dawne Seedan

• MSci (Hons) Biomedical Sciences
• Cortical gamma oscillations: mechanistic insights from in vitro studies

The human brain is known to generate electrical activity (oscillations) of various sizes in different conditions by activating different subunits of the NMDA receptor. In particular, gamma () frequency oscillations have been identified in numerous brain areas in vivo. However, there is a need to understand the mechanisms of this activity in vitro. This project will seek to verify how subunits of the NMDA receptor, and hence oscillation generation and maintenance, vary in age between two groups of experimental animals and through this project, it is hoped that the role of  frequency oscillations in cognitive function can be deduced.

Funding Source: Newcastle University