ERG image montage

Epithelial Research Group

at Newcastle University

ERG Away Day Programmes

ERG Away Day Programme 2006
ERG Away Day Programme 2005
ERG Away Day Programme 2004
ERG Away Day Programme 2003
ERG Away Day Programme 2002
ERG Away Day Programme 2001

ERG Away Day 2006

Thursday 21st September 2006, Grey Street Hotel, Newcastle upon Tyne

Session I

9.20-10.00 Emily Abbot Streptococcus pyrogenes interactions with human epithelia

10.00-10.40 John Sayer Molecular diagnosis, pathogenesis and treatment strategies in cystic kidney diseases

10.40-11.00 Lee McCloy (Roche Diagnostics) Sequence your bacterial genome in a day!

11.00-11.20 COFFEE

Session II

11.20-12.00 Felicity May (Northern Cancer Research Institute) Trefoil proteins: interactions with mucins, other proteins and H. pylori

12.00-12.15 Jeff Pearson Evidence of increased gastric aspiration in acute lung allograft rejection

12.15-12.40 Trevor Jackson Identification of new isoforms of the SGK1 kinase

12.40-13.00 Annemieke Walker/Donald Innes (Invitrogen) The Advantages of the Alexa Fluor Dyes

13.00-13.40 LUNCH

Session III

13.40-14.20 Rob Taylor (Neurology, Neurobiology & Psychiatry) Mitochondrial DNA mutations in human pathology

14.20-15.00 Colin Brown Human proximal tubule cell monolayers - a new tool to study renal xenobiotic secretion

15.00-15.20 Russell Thompson (Merck Biosciences) Enabling Proteomic Research with Novel Proteome Sample Preparation and Analysis Tools

15.20-15.40 COFFEE

Session IV

15.40-16.20 Dianne Ford Nutrient-gene interactions; Lisa Coneyworth Effects of DNA methylation on zinc-regulated gene expression; Kelly Jackson Transcriptional regulation of the zinc transporter ZnT5

16.20-17.00 David Thwaites, Catriona Anderson, Susan Harrison Transporters in the small intestine and neuroblastoma

17.00-17.30 Mark Carlile The Biology of Endogenous Antisense Transcripts; Andi Werner A living proof of molecular Darwinism?

17.30-18.15 Closing remarks and WINE RECEPTION


ERG Away Day 2005

Thursday 15th September 2005, Hatfield College Durham

11.00-11.10 Welcome and IntroductionERG Away Day 2005

1.10-11.50 Andi Werner Natural antisense transcripts and gene regulation

11.50-12.30 Dan Swan Bioinformatics support and facilities at Newcastle

LUNCH 12.30-13.30

13.30-14.10 David Thwaites, David Kennedy, Catriona Anderson Surface pH, dipeptide and amino acid uptake in mouse small intestine

14.10-14.50 Colin Brown The SLC7 family of amino acid transporters

14.50-15.30 Lee McLoy (Roche) The universal probe library Nicola Parsons (Ambion) Experimental tools for microRNA analysis

COFFEE 15.30-16.15

16.15-16.55 Sarah Newbury RNA turnover and its role in developmental processes in Drosophila

16.55-17.45 Barry Hirst, Alison Howard, Imran Tahir The role of glycine in intestinal cell protection

WINE RECEPTION 17.45-18.15

18.15-19.00 Nigel Belshaw (Norwich) Aberrant CpG island methylation as a biomarker of health/disease that is modifiable by diet

Friday 16th September 2005

BREAKFAST 8.00-9.00

9.00-9.40 Vanessa Hall Therapeutic cloning: Curing the uncurable

9.40-10.20 John Sayer The molecular genetics of renal cystic diseases

COFFEE 10.20-11.00

11.00-11.40 Simon Whitehall HIRA nucleosome assembly factors the propagation of repressive chromatin

11.40-12.20 Dianne Ford Epigenetic regulation of Zn metabolism

12.20-13.00 Cerys Huggins (Merck Biosciences) Improving recombinant protein expression in E coli; Damian Wells (Promega) HaloTag technology

LUNCH 13.00-13.45

13.45-14.20 Barry Argent The SLC26 family of anion exchangers in health and disease

14.20-15.00 Judith Hall, Panagiota Milona, Claire Townes Expression and Antimicrobial Activities of Gallinacins 4 and 7. AWAK-the continuing story.

15:00-15:30 Jeff Pearson

15:30-15:35 Closing remarks

5:35-16:15 Round Table (ERG staff)

ERG Away Day 2004

Thursday 16th September 2004, Hatfield College, Durham

11.00-11.15 Welcome and Introduction

11.15-12.00 Andi Werner, Gavin McHaffie, Mark Carlile Transport, adaptors proteins and epigenetics

LUNCH 12.00-13.00

13.00-14.00 David Thwaites, Catriona Anderson, Emily Abbot, David Kennedy

14.00-15.00 Barry Hirst, Imran Tahir, Gerry Siou A role for fimbriae in Streptococcal infection of human tonsils

POSTERS and EXHIBIT 15.00-16.00

16.00-17.00 Amersham Biosciences Utilizing the CodeLink bioarray platform to detect gene expression levels in heritable lysosomal storage disease; Ambion siRNA

17.15-17.45 Colin Brown, Amy Windass Hepatic and renal clearance of the lipid lowering drug rosuvastatin; Rachel Sayer The SLC7 family of amino acid transporters

WINE RECEPTION 17.45-18.15

18.15-19.00 Invited pre dinner speech: Paul Sharp (Surrey) Diet-gene interactions: The effects of dietary trace metals on intestinal iron absorption?

Friday 17th September 2004

BREAKFAST 8.30-9.00

9.00-9.45 Dianne Ford, Louise Pritchett The production and biological activity of isoflavone metabolites; Luisa Watson The impact of genetic polymorphism on isoflavone absorption and metabolism; Kelly Jackson The regulation and function of splice variants of the zinc transporter ZnT5 (SLC30A5).

9.45-10.30 Nick Simmons Functional organisation of the rumen epithelium


11.00-11.45 Invited speaker: David Bassett (Newcastle)

11.45-12.45 Talks from Industry: VWR International Limited; Abgene; Sigma An introduction to Proteomics

LUNCH 12.45-13.30

13.30-14.15 Jeffrey Pearson Jeff the baker

14.15-15.00 Barry Argent Inversin and polycystic kidney disease; Zoltan Rakonczay A novel basolateral HCO3- transport mechanism in pancreatic duct cells

15.00-15.45 Judith Hall The innate immune system of avian epithelia; M. Panagiota Avian b-defensin antimicrobial peptides

Closing remarks 15:45-16:00

ERG Away Day 2003

Thursday 18th September 2003, Hatfield College, Durham

11:00 Welcome Participants of the 2003 ERG Away Day

Session 1 Imaging

11:00–11:20 Georgina Carr The role of CLC-5 in Dent’s disease

11:20–11:40 John Sayer Deaf, dented and donor kidneys

11:40–12:05 Anna Brown Mechanistic and functional changes in Ca2+ entry following retinoic acid-induced differentiation of neuroblastoma cells

12:05–12:25 Fiona Riddoch Calcium signalling in a human neuroblastoma cell line

12:25–13:30 Lunch

Session 2 Transport

13:30–14:00 David Kennedy Amino acid transport by the novel transporter rPAT2

14:00–14:20 Sarah Waring Alternative transcription of the Glyt1 glycine transporter during intestinal response to diet

14:20–14:40 Zoltan Rakonczay pH regulation of human pancreatic duct cells

14:40 – 15:30 Coffee and poster session

Session 3 Interactions

15:30–16:00 Elizabeth Veal (Newcastle) The yeast-2-hybrid system

16:00–16:20 Gavin McHaffie Do iNOS and Shank 3b interact?

16:20–16:40 Gerard Siou Group A streptococcal interaction with human epithelial cells. An in vitro model of tonsil epithelial cell infection?

16:40–17:30 Heiko Peters Region-specific differentiation of the surface ectoderm - the role of Pax9

19:00 Dinner at Restaurant Venezia

Friday 19th September 2003

Session 4 Electrophysiology

9:30–10:15 John Winpenney (Sunderland) Tissue distribution and functional studies of the mCLCA3 (alias Gob-5) protein, a putative calcium-activated chloride channel

10:15–10:35 John Linley Zinc Regulation of an Outwardly Rectyfying Cl- Conductance in Mouse Inner Medullary Collecting Duct Cells (mIMCD-3)

10:35–11:00 Coffee

Session 5 ‘Down and Out’

11:00–11:30 Ambion (Nicola Parsons) Latest news on siRNA

11:30–12:15 Andi Werner Natural antisense RNA

12:15–13:30 Lunch / Posters

Session 6 Aspects Of Digestion

13:30–14:15 Hari Hundal (Dundee) Stress encounters of the lipid kind - The role of ceramide as modulator of insulin action and glucose transport in muscle cells

14:15–14:35 Ruth Cragg The effect of zinc supplementation in human subjects on the expression in small intestine of zinc transporters

14:35–14:55 Kathyrn Atherton The role of xenobiotic-metabolising enzymes in isoflavone metabolism

14:55–15:15 Ian Brownlee Alignates as a source of dietary fibre

15:15–15:35 Chris Nile Isolation and characterisation of novel antimicrobial peptides from the avian gut

ERG Away Day 2002

Thursday 19th September 2002, Hatfield College, Durham

11.00-11.05 Welcome and Introduction

11.05-12.20 Presentations from Industry: Nicola Parsons (Ambion); Liz Homer (Quiagen); Andrew Harrison (Sigma) ERG Away Day 2002

LUNCH 12.30-13.30

13.30-15.00 Intestinal absorption of nutrients:
Barry Hirst
David Thwaites


16.00-17.30 Water and ion transport in the kidney
Dave Marples (Leeds)
Nick Simmons

BREAK with a pint or a glass of wine
The success story of a Newcastle graduate by Lee McCloy (Abgene)

DINNER and BAR 18.30-23.00

Friday 20th September 2002

BREAKFAST 8.30-9.15

9.15-10.45 RNA / protein sorting
Zosia Lightowlers (Newcastle)
Andi Werner


11.15-12.45 Biological and Nutritional Sciences
Dianne Ford
Judith Hall

LUNCH 12.40-13.20

13.20-14.00 Mucus
Jeff Pearson

14.00-15.20 Channels, transporters and disease
Mike Gray
Barry Argent

COFFEE & discussions 15.20-16.00

16.00-16.30 Reports, general discussion, concluding remarks

ERG Away Day 2001

Thursday 13 September 2001, Hatfield College, Durham

12.15-13.15 arrival and registrationParticipants of the 2001 ERG Away Day

13.15-13.20 Welcome

13.20-14.05 A. Werner The various aspects of Na/Pi cotransport
14.05-14.50 John H Robinson (Newcastle) How do T lymphocytes recognize bacterial proteins?

14.50-16.00 Coffee and Poster session

16.00-16.45 John Kirby (Newcastle) T cell interactions with epithelia
16.45-17.30 Barry Hirst Gut epithelial barrier: from nutrient transport to vaccine delivery

18.00-19.15 Dinner

19.30-20.15 David Thwaites Optimisation of nutrient absorption in the human small intestine requires the coordinated activity of multiple transport proteins

20.15-23.00 Drinks and Discussion in the bar area

Friday 14th September 2001

8.30-9.15 Breakfast

9.30-10.15 Mike Gray Epithelial Cl- channels
10.15-11.00 Barry Argent, Angela Wright Cl- channels in the pancreas

11.00-11.30 Coffee and Posters

11.30-12.15 Nick Simmons, John Sayer, Stefan Boese Cl- channels in the kidney

12.30-13.15 Lunch

13.15-14.00 Colin Brown Molecular insight into the targeting of statins
14.00-14.30 Dianne Ford Epithelial zinc transport - a molecular insight

14.30-15.30 Coffee, Group-internal strategic discussion

15.30-16.15 Reports, general discussion

16.15 concluding remarks

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The Physiological Society Epithelia & Membrane Transport Themed Meeting 2009