Newcastle University

Williams Faith M. Evaluation and predictions of dermal absorption of toxic chemicals  International Archives of Occupational and Environmental Health 2004, 77, 150-151

van der Sandt, JJM, Maas, WJM, van Burgsteden, JA, Sartorelli, P, Montomoli, L, Larese, F Payan, J-P, Limaset, JC, Carmichael, P, Kenyon, S, Robinson, E, Dick, I , Nilsen Jb, Schaller K-H, Korinth, G, Cage, S Wilkinson, SC and Williams Faith M. In vitro prediction of skin absorption of caffeine, testosterone and benzoic acid : multicentre comparison study. Regulatory Pharmacology and Toxicology 39 271-2812004

Simon C. Wilkinson, Wilfred J.M. Maas, Jesper Bo Nielsen, Laura C. Greaves, Johannes J.M. van de Sandt, Faith M. Williams Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies submitted International Archives of Occupational and Environmental Health

Francesca Larese Filon, Giovanni Maina, Gianpiero Adami*, Marta Venier*, Nicoletta Coceani**, Rossana Bussani, Marilena Massiccio, Pierluigi Barbieri* and Paolo SpinelliIn vitro percutaneous absorption of cobalt International Archives of Occupational and Environmental Health( 2004) 77 85-89

S. Kezic, W.J. Meuling, I. Jakasa  Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteersInternational Archives of Occupational and Environmental Health in press

Sanja Kezic^, Astrid Janmaat^,Jacob Kruse^, Aart.C. Monster^, Maarten.M. Verberk  Percutaneous absorption of xylene vapour in volunteers during pre steady state and steady state Accepted for publication Toxicology Letters , 153, 273-282 2004,

I.Jakasa, F. Calkoen and S. Kezic  Determination of polyethylene glycols of different molecular weight in the stratum corneum  Journal of Chromatography B, 811, 177-182, 2004

Sanja Kezic, Astrid Janmaat, Jacob Kruse, Aart C. Monster and Maarten M. Verberk  Percutaneous absorption of m-xylene vapour in volunteers during pre- steady and steady state  Toxicology Letters 153,273-282  2004

John Corish and Dara Fitzpatrick Theoretical Models of Percutaneous Absorption .International Conference on Occupational and Environmental Exposures of Skin to Chemicals: Science and Policy (2003)

Fitzpatrick D, Corish J and Hayes B (2004) Modelling skin permeability in risk assessment : the future Chemosphere 55 1309-1314

Francesca Larese, Gianpiero Adami^, , Giovanni Maina, Marta Venier,  Edoardo Reisenhofe¹ LA VALUTAZIONE DELL ASSORBIMENTO PERCUTANEO:  RISULTATI PRELIMINARI DI UNO STUDIO REALIZZATO NELL AMBITO DEL PROGETTO EUROPEO EDETOX Presented at Italian Society of Occupational Hygiene

D.G. Koopman, S. Kezic and M.M. Verberk (2004) Skin reaction and recovery: a repeated sodium lauryl sulphate patch test vs. a 24-h patch test and tape stripping.  British Journal of Dermatology  150  493.

Nielsen JB, Grandjean P, (2004) Criteria for skin notation in different countries Am J Ind Med 45 275-280

Sartorelli, P (2002) Dermal exposure assessment in occupational medicine. Occup. Med 52 151-156

Sartorelli P, Anderson, HR, Angerer J, Corish J, Drexler, H, Goen T, Griffin, P, Hotchkiss, SAM Larese, F, Montomoli L, Perkins J Schmeiz, M van der Sandt J Williams F ( 2000) Percutaneous studies for risk assessment Environ Toxicol Pharmacol 8 133-152   

Nielsen JB, Nielsen F and Sorrenson JA In vitro percutaneous penetration of five pesticides- the effects of molecular weight and solubility characteristics Annals of Occupational Hygiene accepted for publication

M. Venier, G. Adami, F. Larese, G. Maina, N. Renzi  Percutaneous absorption of 5 glycol ethers through human skin in vitro, to be published in Toxicology in vitro ( 2004) Percutaneous absorption of neat and aqueous solutions of 2- butoxyethanol in volunteers International Archives of Occupational and Environmental Health  77, 79-84

Kenyon, Susan, Bhattacharyya J, Benson, CJ and Carmichael PL (2004) Percutaneous penetration and genotoxicity of 4,4-methylenediamine through rat and human skin in vitro Toxicology 196, 65-75

TRANSDERMAL ELECTRICAL RESISTANCE AND ABSORPTION MEASUREMENTS IN A FLOW THROUGH CELL SC WILKINSON, LC GREAVES and FM WILLIAMS PPP Presentation April 2002

HOW WELL CAN ONE EXTRAPOLATE PREDICTIONS WITH SKIN IN VITRO TO IN VIVO ABSORPTION? ARE THE DATA RELIABLE? Faith M WILLIAMS PPP 2002

Physiologically-Based Pharmacokinetic Modelling of the Skin Absorption of N-Methyl-Pyrrolidone in vivo. Mark S. Penney Abstract British Toxicology Society Sept 2002

Percutaneous Penetration studies for risk assessment Faith M Williams, , International Conference of Occupational and Environmental exposures of skin to  Chemicals: Science and Policy 2002

THE USE OF PERCUTANEOUS PENETRATION DATA IN RISK ASSESSMENT: THE EC EDETOX PROJECT Sartorelli P, Montomoli L, Sisinni AG, van De Sandt J, Meuling WJA, Maas WJM, Larese F, Payan JP, Limasset JC, Carmichael P, Kenyon S, Caldwell J, Corish J, Fitzpatrick D, Dick I, Payne M, Shaller KH, Drexler H, , Korinth G, Cage S, O'Connor J, Nielsen JB, Kezic S, Soyei S, Wilkinson S, Williams Faith.M 27^th International Congress on Occupational Health- ICOH 2003 (Iguassu Falls, Brazil, 23-28 February 2003).

Criteria for Skin Notation in an International Perspective Jesper Bo Nielsen, and , Philippe Grandjean,  International Conference of Occupational and Environmental exposures of skin to  Chemicals: Science and Policy 2002

J.J.M. van de Sandt, W.J.M. Maas, J.A. van Burgsteden, P. Sartorelli, L. Montomoli, F. Larese, J.-P. Payan, J.C. Limasset, P. Carmicheal, S. Kenyon, E. Robinson, I. Dick, J.B. Nielsen, K.-H. Schaller, G. Korinth, S. Geh, S. Cage, S. Wilkinson and F.M. Williams (2002). International evaluation of the robustness of in vitro percutaneous absorption studies. Eighth International Conference Perspectives in Percutaneous Penetration, 2-6 April, 2002 (Juan -les-Pins, France). Perspectives in Percutaneous Penetration, p. 126, volume 8a (Ed. K.R. Brain and K.A. Walters).

WJA Meuling, JJM Van de Sandt and L Roza, (2002). Percutaneous Penetration of Caffeine in human volunteers: a mass balance approach Presented at Eighth International Conference Perspectives in Percutaneous Penetration, 2-6 April, 2002 (Juan -les-Pins, France). Perspectives in Percutaneous Penetration, p. 105, volume 8a (Ed. K.R. Brain and K.A. Walters).

W.J.M. Maas, J.J.M. van de Sandt and G. Korinth. Efficiency of microdialysis for the assessment of percutaneous absorption varies between test compounds. Ninth International Conference Perspectives in Percutaneous Penetration, 13-17 April, 2004 (La Grande Motte, France). Perspectives in Percutaneous Penetration, p. 98, volume 9a (Ed. K.R. Brain and K.A. Walters).

G. Korinth, J.J.M. van de Sandt, H. Drexler and W.J.M. Maas. Vergleichbarkeit von Hautpenetrationsuntersuchungen. 44^th annual meeting of the Deutsche Gesellschaft fur Arbeitsmedizin und Umweltmedizin, 21-24 April, Innsbruck, Austria.

J.J.M. van de Sandt. International evaluation of the robustness of in vitro percutaneous absorption studies. Oral presentation at meeting In Vitro Toxicology Industrial Platform. Zeist, The Netherlands, 24 - 25 October 2002.

J.J.M. van de Sandt. Robustness of in vitro percutaneous absorption studies. Oral presentation at the 41th congress of the European Societies of Toxicology. Florence, Italy, 28 September - 1 October 2003. Toxicology Letters 144 (suppl. 1), S 2.

W.J.M. Maas. Efficiency of microdialysis for the assessment of percutaneous absorption varies between test compounds. Oral resentation at Ninth International Conference Perspectives in Percutaneous Penetration, 13-17 April, 2004 (La Grande Motte, France). Perspectives in Percutaneous Penetration, p. 98, volume 9a (Ed. K.R. Brain and K.A. Walters).

Proceedings of the ABD (Working group for occupational and environmental dermatology (oral presentation in Heidelberg, Germany, 11.-13.September 2003): G. Korinth, T. Wellner, K. H. Schaller, H. Drexler: Bewertung der Validitat der in vivo Mikrodialyse anhand von Hautpenetrationsstudien Dermatologie in Beruf und Umwelt (Occupational and environmental dermatology) 2003; 51(1): D27 (Abstract).

 G.Adami, F.Larese, M.Venier, G.Maina, E.Reisenhofer, P. Barbieri: Assorbimento percutaneo di polveri di cobalto: risultati di uno studio realizzato nell ambito del progetto europeo EDETOX, XXI Congresso Nazionale della Societe Chimica Italiana, Torino 22-27 giugno 2003, Atti, Vol.1, AN-CO-057 (2003).

 F. Franco, Valutazione dellassorbimento percutaneo di glicoleteri, degree thesis, 2003.

Wilkinson, S.C. and Williams, F.M. (2002) Effects of experimental conditions on percutaneous absorption of glycol ethers in vitro. International Archives of Environmental and Occupational Health 75:519-527.

Wilkinson, S.C., Greaves, L.C. and Williams F.M. (2002) Transdermal electrical resistance and absorption measurements in a flow through cell. In: Perspectives in Percutaneous Penetration Vol 8B (Brain, K.R. and Walters, K.A. eds) STS Publishing, Cardiff In Press

Greaves, L.C., Wilkinson, S.C. and Williams, F.M. (2002) Factors affecting the percutaneous absorption of caffeine in vitro. Toxicology 178:65-66

Toxicokinetics and metabolism of N-[14C]methylpyrrolidone in male Sprague Dawley rats. A saturable NMP elimination process. Drug Metabolism and Disposition 30, 1418-1424, 2002

Toxicokinetics and metabolism of N-[14C]methylpyrrolidone in male Sprague Dawley rats. In vivo and in vitro percutaneous absorption. Drug Metabolism and Disposition 31, 659-669, 2003

Sartorelli P.: Dermal exposure assessment in Occupational Medicine. Occup. Med. 52: 151-156, 2002

Maina G., Larese F., Sartorelli P., Montomoli L., Boario G., Pollone A., Sisinni A.G., Bagnato E.: RISKOFDERM: The European research project for assessment of occupational skin exposure to chemicals. Med Lav 93: 73-79, 2002 (abs in English)

Montomoli L., Sisinni A.G., Cioni F., Barabesi L., Gilberti M.E., Festa D., Sartorelli P.: Evaluation of the sources of mercury absorption through the study of urinary levels in the general population. Med Lav 93: 184-188, 2002 (abs in English)

Sartorelli P., Montomoli L., Sisinni A.G., Cioni F., Barabesi L., R. Bussani R., Sartorelli E.: In vitro study on the percutaneous absorption of inorganic mercury from contaminated soil. Med Lav 93: 279-285, 2002 (abs in English)

Sartorelli P., Pistolesi P., Cioni F., Napoli R., Sisinni A.G., Bellussi L., Passali G.C., Cherubini Di Simplicio F., Flori L.: Allergic skin and respiratory disease due to polyfunctional aziridine. Med Lav, 94: 285-295, 2003 (abs in English)

Sartorelli P., Montomoli L., Sisinni A.G., Barabesi L., Bussani R., Cherubini Di Simplicio F.: Percutaneous penetration of inorganic mercury from soil: in vitro study. Bull Environ Contam Toxicol (in press)

Montomoli L., Sisinni A.G., Ferraro T., Montinaro L., Sartorelli P.: Cutaneous effects from occupational exposure to fenvalerate and biological monitoring of urinary metabolites. VIII International Conference "Perspectives in Percutaneous Penetration", Antibes Juan-Les-Pins 2-6 Aprile 2002. In Brain K.R. e Walters K.A., Perspectives of Percutaneous Penetration, Vol.8a, STS Publishing Editore, Cardiff 2002, p. 120

Montomoli L., Sisinni A.G., Cioni F., Fimiani M., Pianigiani E., Sartorelli P.: Permeability of cryopreserved and glycerolized skin: in vitro study with a flow through cell system. VIII International Conference "Perspectives in Percutaneous Penetration", Antibes Juan-Les-Pins 2-6 April 2002. In Brain K.R. e Walters K.A. (Eds) Perspectives of Percutaneous Penetration, Vol.8a, STS Publishing Editore, Cardiff 2002, p. 121

Porcelli B., Terzuoli L., Frosi B., Pagani R., Montomoli L., Romeo R., Sartorelli P.: Blood concentrations of lead and erythropoietin. Letter to the Editor, Lab. Clin Med., 139: 125, 2002

Sartorelli P., Scancarello G., Romeo R., Cioni F., Cassano P., Marcian G., Battista G.: Mineralogical analysis of bronchoalveolar lavage fluid as asbestos exposure marker. 27 ICOH, Iguassu Falls - Brazil 23-28 February 2003