Dr. Sirintra Nakjang

Contact information

• Phone number: +44 (0)191 222 7856
• e-mail adress: Sirintra.Nakjang (at) newcastle.ac.uk

Work description

I carried out my PhD research at Newcastle University under the supervision of Dr. Robert Hirt and Prof. Anil Wipat. The main aim of my PhD project was to gain a better understanding of host-microbe interactions, particularly focusing on an in-silico identification of microbial extracytoplasmic protein sequences that may play important roles in the interactions at the host-mucosal surfaces. The project involved the development of a systematic, high-throughput sequence analysis workflow to automate the analysis of all available proteomes.

Currently, I am a research associate at Newcastle University and work in a lab jointly run by Prof. Martin Embley and Dr. Robert Hirt. My current work includes the analysis of a new Microsporidia genome sequence, Trachipleistophora hominis and a comparative genome analysis to understand the evolutionary differences among the Microsporidian linages. My research interests include sequence analysis, comparative genomics, high-throughput analysis workflow development, metabolic pathway reconstruction, evolution of parasites, host-microbe interaction.

Sirintra 's publications

• Collison M, Hirt RP, Wipat A, Nakjang S, Sanseau P, Brown JR. Data mining the human gut microbiota for therapeutic targets. Brief Bioinform. epub (2012). pubmed
• Nakjang S, Ndeh AN, Wipat A, Bolam DN, Hirt RP. A Novel Extracellular Metallopeptidase Domain Shared by Animal Host-Associated Mutualistic and Pathogenic Microbes. PLoS ONE. vol 7 p. doi: 10.1371 (2012). pubmed
• Hirt RP, de Miguel N, Nakjang S, Dessi D, Liu YC, Diaz N, Rappelli P, Acosta-Serrano A, Fiori PL, Mottram JC. Trichomonas vaginalis Pathobiology New Insights from the Genome Sequence. Adv Parasitol. vol 77 p. 87-140 (2011). pubmed
• Kolluru B, Nakjang S, Hirt RP, Wipat A, Ananiadou S. Automatic extraction of microorganisms and their habitats from free text using mining workflows. J Integr Bioinform. vol 8 p. 184 (2011). pubmed