Publications

Publications

Each year, NFRG produces an significant number of publications, of which some are cited many times worldwide. Please find them here sorted by Principal Investigators and a complete list of all our publicated papers.

Selected Publications

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  • cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.View >
  • Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis. View >
  • A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices.View >
  • TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms. View >
  • Platelet GP1ba is a mediator and potential interventional target for NASH and subsequent liver cancer. View >
  • Fibrogenic activity of MeCP2 is regulated by phosphorylation in hepatic stellate cells. View >
  • Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage. View >
  • Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis View >
  • Plasma cell-free DNA methylation: a liquid biomarker of hepatic fibrosis. View >
  • The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple proinflammatory genes. View >
  • MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis. View >
  • The Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation View >
  • Stimulating healthy tissue regeneration by targeting the 5-HT(2B) receptor in chronic liver disease. View >
  • Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in... View >
  • Multigenerational Epigenetic Adaptation of the Hepatic Wound-Healing Response View >
  • Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape View >
  • NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. View >
  • Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis. View >
  • Alcohol directly stimulates epigenetic modifications in hepatic stellate cells. View >
  • A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo. View >
  • Plasma DNA Methylation: A Potential Biomarker for Prognostic Stratification of Liver Fibrosis in Non Alcoholic Fatty Liver Disease. View >
  • The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice. View >
  • The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation. View >
  • The NF-κB subunit c-Rel stimulates cardiac hypertrophy and fibrosis. View >
  • A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB dependent liver regeneration and cancer. View >
  • Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. View >