People
We are a highly interactive group of researchers who focus on eukaryotic Cell Division Biology, but approach it from a different perspectives using a variety of techniques (including cell biology, structural biology, genetics, biochemistry, drug discovery, insights from patient care) and model systems (mammalian cells in culture, human and mouse oocytes, nematode worms, budding yeast and flies).
Owen Davies
- Wellcome Trust and Royal Society Sir Henry Dale Fellow
- Newcastle University Biosciences Institute
- Email: owen.davies@ncl.ac.uk
- Telephone: +44 (0) 191 208 5828
- The molecular basis of mammalian meiosis.
The structure and function of the human synaptonemal complex.
Jane Endicott
- Professor of Cancer Structural Biology
- Newcastle University Translational and Clinical Research Institute
- Email: jane.endicott@ncl.ac.uk
- Telephone: +44 (0) 191 208 4422
- Mechanisms controlling the eukaryotic cell cycle.
Use of X-ray crystallography to determine structures for the protein complexes that drive cell cycle progression.
Christine Harrison
- Professor of Childhood Cancer Cytogenetics
- Newcastle University Translational and Clinical Research Institute
- Email: christine.harrison@ncl.ac.uk
- Telephone: +44 (0) 191 208 2237
- Genetics of acute leukaemia
Mechanisms underlying complex genome rearrangement in leukaemia
Mary Herbert
- Professor of Reproductive Biology
Honorary Consultant Clinical Scientist - Newcastle University Biosciences Institute
- Email: mary.herbert@ncl.ac.uk
- Telephone: +44 (0) 191 213 8213
- Chromosome biology of oocytes and early embryos.
Improving the treatment and understanding of infertility.
Extending reproductive technologies to prevent transmission of disease.
Jonathan Higgins
- Professor of Eukaryotic Molecular Cell Biology
Theme Leader - Cell Division Biology Group - Newcastle University Biosciences Institute
- Email: jonathan.higgins@ncl.ac.uk
- Telephone: +44 (0) 191 208 7431
- Chromosome segregation in mitosis.
Histone modifications during cell division.
Epigenetic inheritance through cell division.
Jun-yong Huang
- Lecturer
- Newcastle University Biosciences Institute
- Email: junyong.huang@ncl.ac.uk
- Telephone: +44 (0) 191 208 3561
- Mitotic checkpoint signalling in human cells and Drosophila.
Drug discovery.
Mark Levasseur
- Senior Research Associate
- Newcastle University Biosciences Institute
- Email: mark.levasseur@ncl.ac.uk
- Telephone: +44 (0) 191 208 3481
- Histone modifications in human cell division.
Meiotic chromosome segregation.
David Lydall
- Professor of Genome Stability
- Newcastle University Biosciences Institute
- Email: david.lydall@ncl.ac.uk
- Telephone: +44 (0) 191 208 5318
- Telomeres, DNA repair and DNA replication.
Suzanne Madgwick
- Wellcome Trust Career Re-entry Fellow
- Newcastle University Biosciences Institute
- Email: suzanne.madgwick@ncl.ac.uk
- Telephone: +44 (0) 191 208 8723
- Control of metaphase exit in oocytes and mitotic cells.
Martin Noble
- Professor of Biomolecular Structure & Anticancer Drug Design
- Newcastle University Translational and Clinical Research Institute
- Email: martin.noble@ncl.ac.uk
- Telephone: +44 (0) 191 208 4466
- Structure-function of protein complexes regulating transcription and the eukaryotic cell cycle.
Kinase inhibitor design and development.
Josana Rodriguez Sanchez
- Senior Lecturer
- Newcastle University Biosciences Institute
- Email: josana.rodriguez@ncl.ac.uk
- Telephone: +44 (0) 191 208 8143
- Polarity and asymmetric cell division in nematode embryos.